Resumen
The aim of this study is to report on the impact of physical activity in a palliative manner on the quality of life of people with Alzheimer's disease (AD). A literature review was conducted using scientific journal articles, theses, dissertations, and scientific websites that were evaluated for the present study. The bibliographic survey was carried out by consulting the following scientific databases: PubMed, Scielo, BVS Brasil. The search was retrospective, limiting itself to scientific papers published from February 2010 to February 2023. Physical activity can delay the expression of symptoms and cognitive impairment of AD, as well as increase protective mechanisms such as the release of neurotrophins and the hormone irisin. The combination of drug therapy with physical activity can also improve the quality of life of patients. Some studies indicate that light and moderate activities can contribute to the reduction of deficits in daily living activities and attenuate sleep disorders. Other studies show that physical activity can improve cognitive function, balance, and reduce the risk of falls in elderly people with AD. Walking seems to be a particularly beneficial physical activity for patients with AD. Although the studies presented in this review strongly indicate the benefits of physical activity for patients with AD, more research is needed to better elucidate the pathophysiology and treatment of the disease.
Citas
AGUIAR P, MONTEIRO L, FERES A, GOMES I, MELO A. Rivastigmine transdermal patch and physical exercises for Alzheimer’s disease: a randomized clinical trial. Current Alzheimer Research. 2014;11(6):532-7.
ARCOVERDE C, DESLANDES A, MORAES H, ALMEIDA C, ARAUJO NB, VASQUES PE, SILVEIRA H, LAKS J. Treadmill training as an augmentation treatment for Alzheimer 's disease: a pilot randomized controlled study. Arquivos de Neuro-Psiquiatria. 2014 Mar;72(3):190-6.
BONDI MW, EDMONDS EC, SALMON DP. Doença de Alzheimer: passado, presente e futuro. Journal of the International Neuropsychological Society, 23 de Outubro, 2017.
BRASIL. Ministério da Saúde. Biblioteca Virtual em Saúde - Conhecer a demência, conhecer o Alzheimer: o poder do conhecimento – Setembro, Mês Mundial do Alzheimer, 2021. Disponível em: https://bvsms.saude.gov.br/conhecer-a-demencia-conhecer-o-alzheimer-o-poder-do-conhecimento-setembro-mes-mundial-do-alzheimer/. Acesso em: 27 de dezembro de 2022.
BRASIL. Ministério da Saúde. Portaria Conjunta Nº 13, de 28 de Novembro de 2017, Brasília 2017.
BRASIL. Ministério da Saúde. Biblioteca Virtual em Saúde - Qual o tratamento para Alzheimer? – Fevereiro, Mês Mundial do Alzheimer. 2023. Disponível em: https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/a/alzheimer/tratamento. Acesso em: 01 de março de 2023.
BUSANELLO, J. Atividade física e a doença de Alzheimer. Orientadora: Ms. Fabiana Ritter Antunes. 2015. Trabalho de Conclusão de Curso (exigência parcial para obtenção do título de Bacharel em Educação Física) – Faculdade de Educação Física, Universidade Regional do Noroeste do Estado do Rio Grande do Sul, Santa Rosa, 2015.
CHRISTOFOLETTI, Gustavo et al. Physical activity attenuates neuropsychiatric disturbances and caregiver burden in patients with dementia. Clinics, v. 66, p. 613-618, 2011.
DI SANTO SG, PRINELLI F, ADORNI F, CALTAGIRONE C, MUSICCO M. A meta-analysis of the efficacy of donepezil, rivastigmine, galantamine, and memantine in relation to severity of Alzheimer's disease. Journal of Alzheimer's Disease, 2013.
ETNIER JL, LABBAN JD, KARPER WB, WIDEMAN L, PIEPMEIER AT, SHIH CH, et al. Innovative Research Design Exploring the Effects of Physical Activity and Genetics on Cognitive Performance in Community-Based Older Adults. Journal of Aging and Physical Activity. 2015; 23(4):559-68.
HERNANDEZ SS, COELHO FG, GOBBI S, FLORINDO S. Efeitos de um programa de atividade física nas funções cognitivas, equilíbrio e risco de quedas em idosos com demência de Alzheimer. Brazilian Journal of Physical Therapy. 2010;14(1):68-74.
KAMADA, M et al. Correlação entre exercício físico e qualidade de vida em pacientes com doença de Alzheimer. Revista da Sociedade Brasileira de Clínica Médica, 2018;16(2):119-122.
LOURENÇO, M; FELICE, F; FROZZA, R L. FNDC5 / irisina ligada ao exercício resgata plasticidade sináptica e defeitos de memória nos moldes de Alzheimer. Nature, 25 de janeiro de 2019.
NASCIMENTO CM, AYAN C, CANCELA JM, GOBBI LT, GOBBI S, STELLA F. Effect of a multimodal exercise program on sleep disturbances and instrumental activities of daily living performance on Parkinson’s and Alzheimer’s disease patients. Geriatrics & Gerontology International. 2014;14(2):259-66.
NOGUEIRA IN, DA SILVA TG, MONTEIRO ER, DE MIRANDA MJC. Os benefícios do exercício físico no tratamento do Alzheimer. In: de Miranda MJC, Monteiro ER. Exercício Como Ferramenta Adjuvante Para Promoção de Saúde. Rio de Janeiro-RJ: Epitaya, 2021. pg.(37-43).
PANIZZA, R. Como Exercícios Físicos ajudam no tratamento do Alzheimer. Portal do Idoso. Organizador: Dr José Eduardo Martinelli, 2017.
PITKÄLÄ KH, PÖYSTI MM, LAAKKONEN ML, TILVIS RS, SAVIKKO N, KAUTIAINEN H, et al. Effects of the Finnish Alzheimer disease exercise trial (FINALEX): a randomized controlled trial. JAMA Internal Medicine. 2013;173(10):894-901.
RIANI, JL. Exercícios físicos ajudam a conter o mal de Alzheimer. 2012.
SERENIKI, A.; VITAL, M.A.B.F. Alzheimer's disease: pathophysiological and pharmacological features. Trends in Psychiatry and Psychotherapy. Porto Alegre, v. 43, n. 2, dez. 2021.
THE ALZHEIMER’S ASSOCIATION. 2021 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia, 2021 March. 17(3), 327–406.
WINCHESTER J, DICK MB, GILLEN D, REED B, MILLER B, TINKLENBERG J, et al. Walking stabilizes cognitive functioning in Alzheimer’s disease (AD) across one year. Archives of Gerontology and Geriatrics. 2013;56(1):96-103.
WORLD ALZHEIMER REPORT 2018. The state of the art of dementia research: New frontiers. Alzheimer’s Disease International (ADI), London.
YU F, BRONAS UG, KONETY S, NELSON NW, DYSKEN M, JACK C JR, et al. Effects of aerobic exercise on cognition and hippocampal volume in Alzheimer’s disease: study protocol of a randomized controlled trial (The FIT-AD trial). Trials. 2014;15:394.
ZIDAN M, ARCOVERDE C, ARAÚJO NB, VASQUES P, RIOS A, LAKS J, DESLANDES A. Alterações motoras e funcionais em diferentes estágios da doença de Alzheimer / Motor and functional changes in different stages of Alzheimer 's disease. Revista de Psiquiatria Clínica. 2012;39(5):161-5
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.